The collection consists of letters written mostly by Isaac White (1837-1889) to his wife, Mary Virginia "Jinnie" Day White, while he served with the Confederate Army as an assistant surgeon during the American Civil War. Many of the letters are written while encamped along the Shenandoah Valley. Other papers include literature gathered by Bess Duvall White Snead, White's grand-daughter, in her search for military information about Isaac White.