The collection contains both material related to Thomas W. Colley's daily life in Abingdon, VA, and to Colley's service as a Confederate soldier in the Civil War. Materials include correspondence, financial documents, such as ledgers, receipts, and deeds, temperance society sermons, electoral cards, a Veteran's Meeting minute book, Civil War reminiscences, and a roll for the First Virginia Company D Volunteer Cavalry's wounded and dead for 1861. The majority of the collection dates from 1860 to 1920.

Much of the correspondence occurs between Thomas Colley and his extended family, except for Colley's business correspondence. The letters dating to the Civil War are typed transcriptions rather than the original. Later letters, however, that make reference to and reminisce about the Civil War are original.