This collection consists of a single accounts ledger from Meade & Baker, a pharmaceutical business in Richmond, Virginia during the latter half of the nineteenth century. Containing more than 600 pages, the ledger appears to be a daybook, recording customer names and addresses, dates of purchases, itemized lists of purchases, and payments. The store's sales consisted almost entirely of pharmaceuticals and related health and beauty goods, but the ledger also records sales for such household items as spices, chewing tobacco, stamps, and pencils. Many of the account entries made during the 1860s illustrate rampant inflation within the Confederacy. The price recorded for a toothbrush in February 1861, for example, is 25 cents, while a January 1865 entry records the price for that same article as 12 dollars.

That the ledger contains account information only for customers outside of Richmond (including a number of customers in other states) suggests that the volume may have been used to record only mail-order purchases. This theory is supported by the fact that this single ledger enumerates an entire decade's worth of sales, far too few for a company that has been described as one of the largest drugstores in nineteenth-century Richmond.