The Hampton D. Smith Collection collection contains research and lab tests pertaining to the formation of undiscovered carboranes and nitriles created by Smith and other collaborators. The collection contains raw data spanning a period of over fifteen years (1974-1990), and several formal proposals pertaining to theories developed from that data. The correspondence in this collection is primarily between Smith and chemists at other prominent universities and colleges, and discuss the possible theories regarding the synthesis and formation of carboranes.