Anthony K. Simmons was born on March 11, 1810 in Virginia. He married Sophia Bower (1811-1885) in Botetourt County in January 1835; the couple lived in the western district of Botetourt County and had nine children, including William and Edmund. A farmer, Simmons also served as a justice of the peace. He died October 2, 1886. Simmons' surname appears in some records as "Simmon" and his letter of July 17, 1862 is signed in this manner.

William Bower Simmons was born in Botetourt County on August 29, 1838. A Roanoke College student at the outbreak of the American Civil War, he enlisted in Company A, 28th Virginia Infantry on May 15, 1861. Simmons was shot in the back at Howlett's House on June 18, 1864 and recovered in a Richmond hospital. Following the war, he served as a Botetourt County supervisor and judge for many years. William Simmons died on November 30, 1917.

Edmund O. Simmons, younger brother of William B., was born in Botetourt County, Virginia, on July 14, 1843. He enlisted as a private in Company A, 28th Virginia Infantry on August 5, 1861. He was was wounded in the Battle of Gaines' Mill on June 27, 1862 and died in a Richmond hospital on August 5.