The collection include business transactions, land surveys, and general store accounts (1745-1789) relating to William and Susannah Smith Preston; correspondence, business transactions, and notes on farm affairs (1782-1828) relating to their son, John Preston; correspondence and land surveys (1840-1882) relating to John, William A., and Alfred G. Preston; correspondence (1848-1861) relating to William Ballard Preston; and a day book (1789-1820) of the Prestons of Washington County.