The collection contains items, which belonged to or were collected by Harold C. Cox during his time as a student at Virginia Agriculture and Mechanical College and Polytechnic Institute from 1922-1926, and his continued experiences with the university as alumnus, primarily from the 1970s and 1980s.

The photograph collection at Special Collections and University Archives consists primarily of historical photographs of Virginia Tech, dating back to the 1890s. The collection is also home to historic images of Blacksburg, Montgomery County, the New River Valley, and Southwest Virginia in general. A photograph collection of faculty and staff from the university is maintained separately.