This collection contains the papers and artifacts of an interrelated family prominent in Blacksburg's history. It includes the American Civil War letters of Confederate surgeon Dr. Harvey Black, the Civil War diary of hospital steward John S. Apperson, cotton books and correspondence of Germanicus Kent, nineteenth-century account books of a Blacksburg general store, 1912 European travel diary, and the political scrapbooks of State Senator and Attorney General Harvey B. Apperson.

The John F. Crosby Papers collection contains John Crosby's research, letters of inquiry, correspondence, and genealogy charts pertaining to his manuscript "Brother vs. Brother: Divided Families in the Civil War.

The collection consists of a daybook with notes from a genealogy on the Hans Joist Hite Family.

The collection consists of a daybook containing the notes from a genealogy on the Olive Family.

Photocopies of genealogical research and records, including family Bible records, family group sheets, and pedigree charts relating to ancestors of Martha Ann Hite Tant, including the Agee, Brown, Davenport, Davidson, Floyd, Haden, Harman, Hite/Hight, Linkous, Marrs, May, Mills, Owen(s), Preston, Salmon(s), Scott, Shelton, and Trollinger families, of Henry, Montgomery, Pittsylvania, and Tazewell counties, Virginia, and elsewhere.

This collection has photocopies of four family record pages from the Henry Wysor family Bible. The papers list the births, deaths, and marriages of the Wysor family line from the 1770s-1960s, starting with Henry Wysor (1755-1844) and his wife Barbary An Ripseed (ca. 1758-1837).